IL-17 receptor signaling and T helper 17-mediated autoimmune demyelinating disease
نویسندگان
چکیده
منابع مشابه
IL-17/IL-17 receptor system in autoimmune disease: mechanisms and therapeutic potential.
IL-17 (interleukin-17), a hallmark cytokine of Th17 (T-helper 17) cells, plays critical roles in host defence against bacterial and fungal infections, as well as in the pathogenesis of autoimmune diseases. The present review focuses on current knowledge of the regulation, functional mechanisms and targeting strategies of IL-17 in the context of inflammatory autoimmune diseases. Evidence shows t...
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ژورنال
عنوان ژورنال: Trends in Immunology
سال: 2011
ISSN: 1471-4906
DOI: 10.1016/j.it.2011.02.007